Dr David Howell studied medicine at University College London, and completed specialist training in General Medicine, Respiratory Medicine and Critical Care in London. He was previously a Medical Research Council Research Fellow at the Centre for Respiratory Research (CRR) at University College London and was awarded a PhD for his work on the role of coagulation proteases in the pathogenesis of inflammatory and fibrotic lung disease. He continues to have an active role in research projects and clinical trials. He works predominantly as a Consultant in Critical Care and Acute Medicine and is currently the Divisional Clinical Director for Critical Care at UCLH.
(i) Absence of Proteinase-Activated Receptor-1 Signaling Affords Protection from Bleomycin-Induced Lung Inflammation and Fibrosis. DCJ Howell, RH Johns, JA Lasky, B Shan, CJ Scotton, GJ Laurent, RC Chambers. The American Journal of Pathology. 2005 May;166(5):1353-65.
(ii) Mass Casualty Incidents (MCI): Are NHS Staff prepared? An Audit of One NHS Foundation Trust. CS Milkhu, DCJ Howell, PA Glynne, L Langmead, D Raptis, H Booth, V Datta. Emerg Med J. 2008 Sep;25(9):562-4.
(iii) New Advances in the Pathogenesis and Treatment of Idiopathic Pulmonary Fibrosis. David CJ Howell, Robin Johns and Geoffrey J Laurent. Timely Topics in Respiratory Medicine (epub), Jan 2008.
(iv) Pulmonary epithelium is a prominent source of proteinase-activated receptor-1-inducible CCL2 in pulmonary fibrosis. Mercer PF, Johns RH, Scotton CJ, Krupiczojc MA, Königshoff M, Howell DC, McAnulty RJ, Das A, Thorley AJ, Tetley TD, Eickelberg O, Chambers RC. Am J Respir Crit Care Med. 2009 Mar 1;179(5):414-25. Epub 2008 Dec 5.
(v) H1N1 Pneumonitis Treated with Intravenous Zanamivir. Kidd IM, Down J, Nastouli E, Shulman R, Grant PR, Howell DCJ, Singer M. Lancet. 2009 Sep 19;374(9694):1036. Epub 2009 Sep 3.
(vi) Pneumonia Caused by Atypical Pathogens. Amelia O Dunscombe and David CJ Howell. Accepted for publication British Medical Journal, e-learning module 2010.