Sarcoma studies 

Listed below are sarcoma studies currently being run through the UCLH Cancer Clinical Trials Unit. Please note this list can be ordered by the shortened trial name, trial status or tumour type by clicking on the header of the relevant column.
Trial nameFilter
A4021020Closed to Recruitment
A phase 1/phase 2 study of CP-751,871 in patients with relapsed and/or refractory Ewing’s Sarcoma Family of Tumours
Ewing’s Sarcoma
Axi-STS studyRecruiting
A clinicopathological phase II study of axitinib in patients with advanced angiosarcoma and other soft tissue sarcomas
Angiosarcoma, soft tissue sarcomasClick here
BODISRecruiting
Quantifying Disease Burden in patients with sarcoma by monitoring tumour-specific genomic rearrangements
Osteosarcoma
CAMN107G2301Closed to Recruitment
A randomized, open-label, multi-centre phase III study to evaluate the efficacy and safety of nilotinib vs imatinib in adult patients with unresectable or metastatic gastrointestinal stromal tumours (GIST)
GIST
CASPSIn Set-Up
A Phase II Trial of Cedirinib in the Treatment of Patients with Alveolar Soft Part Sarcoma
Alveolar Soft Part SarcomaClick here
EuroEwing 99Recruiting
European Ewing Tumour Working Initiatives National Group: Ewing Tumour Studies 1999
Ewing’s SarcomaClick here
EORTC 62024Closed to Recruitment
Intermediate and high risk localised completely resected gastrointestinal stromal tumours (GIST) expressing KIT receptor: A controlled randomised trial of adjuvant Imatinib Mesylate (Glivec) versus no further therapy after complete surgery.
GISTClick here
EPPSSG RMS2005Recruiting
Study of the treatment of rhabdomyosarcoma in childhood and adolescence
rhabdomyosarcomaClick here
EURAMOS 1Closed to Recruitment
A Randomised Trial of the European and American Osteosarcoma Study Group to Optimise Treatment Strategies for Resectable Osteosarcoma Based on Histological response to Pre-operative Chemotherapy
OsteosarcomaClick here
GeDDiSRecruiting
A prospective randomised controlled phase III trial of gemcitabine and docetaxel compared with doxorubicin as first line treatment in previously untreated advanced unresectable or metastatic soft tissue sarcomas
Soft Tissue SarcomaClick here
GLU-1Recruiting
A randomised, cross-over, phase II study, to investigate the efficacy and safety of glucarpidase for routine use after high dose methotrexate in patients with bone sarcoma
OsteosarcomaClick here
Infinity IPI-926-04 (Hedgehog)Recruiting
A Phase 2, Double-Blind, Placebo-Controlled Study Evaluating the Efficacy and Safety of IPI-926 in Patients with Metastatic or Locally advanced (unresectable) Chondrosarcoma
Chondrosarcoma
OTISRecruiting
Oral Treosulfan in Ewing’s Sarcoma: A Phase II Study to determine the efficacy and safety of conventional dose oral Treosulfan in patients with advanced pre-treated Ewing’s Sarcoma.
Ewing’s SarcomaClick here
P04720Closed to Recruitment
A study to determine the activity of SCH 717454 in subjects with Osteosarcoma or Ewing’s Sarcoma that has relapsed after standard systemic therapy.
Ewing’s Sarcoma, Osteosarcoma
Pfizer A6181036/SUGENClosed to Recruitment
A treatment protocol for patients with gastrointestinal stromal tumour who are ineligible for participation in other SU011248 protocols and are refractory to or intolerant of imatinib mesylate
GIST
SARC011Closed to Recruitment
SARC Global Collaboration: A phase II trial of R1507, a recombinant human monoclonal antibody to the insulin-like growth factor-1 receptor for the treatment of patients with recurrent or refractory Ewing’s Sarcoma, osteosarcoma, synovial sarcoma, rhabdomyosarcoma and other sarcomas
Ewing’s Sarcoma, osteosarcoma, synovial sarcoma, rhabdomyosarcoma and other sarcomas
EORTC 62092 (STRASS)In Set-Up
A phase III randomized study of preoperative radiotherapy plus surgery versus surgery alone for patients with Retroperitoneal sarcoma (RPS)
Retroperitoneal sarcoma
SUCCEEDClosed to Recruitment
A pivotal trial to determine the efficacy and safety of AP23573 when administered as maintenance therapy to patients with metastatic soft tissue or bone sarcomas.
Soft Tissue Sarcoma, Bone Sarcoma
VORTEXRecruiting
VORTEX Randomised trial evaluating impact of changes in dose & amp; volume of postoperative radiotherapy on morbidity and limb function in adult patients with extremity soft tissue sarcoma
Soft Tissue SarcomaClick here